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Combine the white chocolate and heavy cream in a small microwave-safe bowl. Heat the mixture in 15-second intervals with microwave set to 50% power. Stir after each interval until chocolate is melted and mixture is smooth.
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Set aside to cool slightly while you proceed with the filling.
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Place the cream cheese in a large mixing bowl and beat with an electric mixer on medium speed for 5 minutes, scraping down the sides of the bowl as needed. Add the sugar and beat well.
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Add the eggs 1 at a time, beating well after each addition, then beat in the scraped vanilla beans, vanilla, and salt.
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Slowly beat in the white chocolate-cream mixture until fully combined. Use a rubber spatula to stir up from the bottom of the bowl several times, making sure everything is properly mixed.
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Pour the filling into the crust and smooth the top.
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Pour a half-inch of water into a roasting pan (or any large rimmed baking pan) and carefully place the pan in the oven.
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Set the cheesecake in the middle of the pan. Bake 1 hour and 45 minutes to 2 hours, until just the center of the cheesecake jiggles when you tap the pan.
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Remove cheesecake from the oven and cool to room temperature. Cover loosely with plastic wrap and refrigerate overnight.